Introduction: The chemical composition of various tissues depends on the functional load of tissues, the general metabolism of the body and the nature of the food consumed by them.

Aim: The purpose of this experiment is to study the changes in the trace element composition of the testes of laboratory animals (for example, cellular dyshydria).

Materials and methods: We studied 24 adult male rats, which were divided into two series: intact (control) and experimental. The latter is divided into 3 groups, 6 animals in each depending on the degree of dyshydria: mild, moderate and severe. Experimental animals throughout the study received granular feed and hypertonic sodium chloride solution 12%. Collection of animal testes was performed in accordance with unified methods. Chemical analysis of the removed organs was performed by the method of spectral analysis in the morphological laboratory of the Department of Morphology on the atomic absorption spectrophotometer C-115M1 according to the generally accepted method. The content of the most active trace elements in the testes of rats was studied: copper, iron, zinc, magnesium, chromium and lead.

Results. The results of the study suggest that in experimental animals that were in conditions of mild dehydration, compared with the control series, the average values of copper (4.08 ± 0.018 and 4.11 ± 0.101 μg / g), magnesium (5.75 ± 0.018 and 5.91 ± 0.121 μg / g), chromium (3.82 ± 0.011 and 3.83 ± 0.013 μg / g), lead (1.90 ± 0.064 and 1.97 ± 0.030 μg / g), respectively, not have a significant statistical difference, but the amount of iron and zinc increases by 10% and 12%, respectively. During further study at the end of the 20-day period (average degree of cellular dehydration), the indicators of copper, magnesium, chromium, lead also do not change significantly. But the amount of iron and zinc increases significantly compared to the control group by 52% and 35%, respectively. Animals with severe dyshydria underwent significant changes in the content of elements such as iron, zinc and magnesium, increasing by 45%, 23% and 6%, respectively, control series. But again, there were no statistically significant changes in all other elements.

Conclusions. Thus, after analyzing all the indicators we studied, we have the right to say that in the testes of experimental animals under the influence of cellular dehydration of various kinds, the most statistically significant changes occur with the content of chemical elements such as iron, zinc and magnesium.

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