Introduction: In Ukraine, the incidence of malignant brain tumors is 5.4 cases per 100 thousand population according to 2019 data. In particular, women have this figure is 4.8 per 100 thousand population, men – 6.1 per 100 thousand people. In Ukraine, there are no uniform standards for the diagnosis of tumors in such patients at an early stage, so the urgent issue is the development of protocols and recommendations that are mandatory for doctors of various specialties.

Aim: To develop screening methods for diagnosing brain tumors in the early stages for better treatment of brain tumors.

Materials and object of research: Domestic and foreign scientific publications were analyzed to develop screening methods. These studies were analyzed to determine the general principles of pathogenesis and symptom development.

Results: Based on the analysis of the work, it was found that under the influence of a certain provoking factor there are changes in the group of cells of the gray matter of the brain of a certain differentiation, resulting in impaired control of the mitotic spindle and uncontrolled cell division. It was also found that the high frequency of exposure to adverse factors on the mitotic process, affects the stage of telophase or anaphase, as a consequence, the tumor will lose its contours and will be more malignant. Histologically, according to the functional purpose in the gray matter of the brain there are two main types: trophic and conductive. And depending on the number of cells affected in the patient, may be disturbed by increased fatigue, decreased efficiency, signs of hypoxia, inhibition, tachyarrhythmia, reflex disorders, as well as possible functional disorders of the system “hypothalamus-pituitary-executive organs”. Therefore, to reduce the risk of developing a tumor, it is necessary to find out a detailed history to identify provoking factors, their time of exposure depending on age and, if possible, to isolate from them.

Conclusions: Currently, there is a demographic regression of the population in Ukraine – caused by various features, partly due to late detection of diseases and subsequent ineffective treatment, so there is a need to write a national protocol for screening and diagnosis of patients directly with brain tumors. The development of appropriate screening tests can significantly improve the state of medical care for such patients.