Smorodska O., Moskalenko Yu, Kuzmenko V., Moskalenko Yu.
Department of Oncology and Radiology,
Medical Institute, Sumy State University, Ukraine
Toufik’s Medical Journal
Volume 1, Supplement 1, November 2021
Abstract from Biomedical Perspectives III
Introduction: Amount of malignant tumors are increasing all the time. Nowadays scientists are trying to develop algorithm to predict prognosis for patients with malignant tumors as well as found factors that influence on survival in patient that performed surgery. Lung cancer as one of the most common reason of death is not exception.
Aim: To determine prognostic factors that influence on duration of life in patient surgically resected non small cell lung cancer.
Materials and methods: 52 source documents of patients that performed surgery during 2016-2018 with early stages (IB – IIIA) of lung cancer were studied during the period 2016-2021. All patients got 4 courses of adjuvant chemotherapy depending on hystological type of the tumor. Statistic and retrospective methods of data analysis were used.
Results: We found out that 19 out of 52 patients (36,5%) had disease relapse and died during the period of investigation. 15,8% had disease recurrence during the first year after surgery, 47,3% had disease recurrence from one to two year after surgery, 5,3% had disease recurrence from two to three years after surgery, 31,6% had disease recurrence after 3 or more years after surgery. It is important to highlight that period from primer diagnostic and surgery performed was not more then 1 month in all cases. Among died patients men were 94,7%, while woman – 5,3%. All of died patients were smokers with tumor size 5 cm and bigger. Most patients that died (57.9%) were older then 60 years old. In all died patients local or distant metastasis were determined. Most common locations of metastases were lungs, lymphatic nodules of the mediastinum, liver and kidneys. 68,4% of died patient performed right side surgery. Among died patients 42,1% had adenocarcinoma, while squamos carcinoma was determined in 57,9% cases.
Conclusions: We found that among patients that had disease recurrence 68% died during first three years after surgery. During the investigation we also found that poor prognosis has smokers with male gender in the age over 60 years old. Most of them had squamos lung cancer and primary tumor size 5 and more cm on the right side.